Selective Alpha-2 agonists

Question 1

Indications of CLONIDINE

Answer 1

• treatment of hypertension (not first line)
• hypertensive crisis!
• alcohol & opiate withdrawal,; cessation of smoking
• perianesthetic medication
• sedation and analgesia in intensive care, adjuvant analgesic (epidural, intrathecal)
• ADHD
• glaucoma
• diarrhea in diabetics

(This is from lecture !! Sketchy said : hypertension, hypertensive crisis, ADHD)
Sedierung und analgesie- nur eingeschränkt

Question 2

Tizanidine

Answer 2

Centrally acting skeletal muscle relaxant

-an alpha -2 receptor agonist

Sketchy micro : To X-tine = Tizanidine

used in : Multiple sclerosis& ALL to treat muscle spasms, Mach orthopädischen Operationen, Muskelverspannungen z.b. im Bereich der Wirbelsäule