1
Q
What are the clinical applications of renin inhibitors?
A
-hypertension
2
Q
What are the clinical applications of ACE inhibitors?
A
- hypertension
- heart failure
- diabetic neuropathy
- MI
3
Q
What are the clinical applications of angiotensin II receptor antagonists?
A
- hypertension
- diabetic neuropathy
- heart failure
- MI
- prevention of stroke
4
Q
What are the clinical applications of BNP?
A
-acutely decompensated heart failure
5
Q
What are the clinical applications of vasopression receptor 2 antagonists?
A
- euvolemic hyponatremia
- SIADH
- heart failure
- cirrhotic ascites
- autosomal dominant polycystic kidney disease
6
Q
What are the clinical applications of carbonic anhydrase inhibitors?
A
- high-altitude sickness
- heart failure
- epilepsy
- glaucoma
7
Q
What are the clinical applications of osmotic diuretics?
A
- cerebral edema
- increased intraocular pressure
- prophylaxis of oliguria in acute renal failure
8
Q
What are the clinical applications of loop diuretics?
A
- hypertension
- acute pulmonary edema
- edema associated with heart failure, hepatic cirrhosis, or renal dysfunction
- hypercalcemia
- hyperkalemia
9
Q
What are the clinical applications of thiazide diuretics?
A
- hypertension
- adjunct in edema states associated with heart failure, hepatic cirrhosis, renal dysfunction, corticosteroid and estrogen therapy
10
Q
What are the clinical applications of spironolactone and eplerenone?
A
- hypertension
- edema associated with heart failure, liver cirrhosis (with or without ascites), or nephrotic syndrome
- hypokalemia
- primary aldosteronism
- acne vulgaris (spironolactone)
- female hirsutism (spironolactone)
11
Q
What are the clinical applications of amiloride and triamterene?
A
- hypertension
- Liddle’s syndrome
Pharmacology Chapter 20
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