Contraindications

Question 1

What are the contraindications of renin inhibitors?

Answer 1

• pregnancy
• hyperkalemia
• history of angioedema
• cyclosporine therapy

Question 2

What are the contraindications of ACE inhibitors?

Answer 2

• history of angioedema
• bilateral renal artery stenosis
• renal failure
• pregnancy

Question 3

What are the contraindications of angiogensin II receptor antagonists?

Answer 3

• bilateral renal artery stenosis

- pregnancy

Question 4

What are the contraindications of BNP?

Answer 4

• cardiogenic shock

- systolic blood pressure less than 90

Question 5

What are the contraindications of vasopression receptor 2 antagonists?

Answer 5

• concurrent use of potent CYP 34A inhibitors

- hypovolemic hyponatremia

Question 6

What are the contraindications of carbonic anhydrase inhibitors?

Answer 6

• adrenal gland failure
• chronic angle-closure glaucoma
• cirrhosis
• hyponatremia/hypokalemia
• hyperchloremic acidosis
• severe hepatic or renal disease

Question 7

What are the contraindications of osmotic diuretics?

Answer 7

• anuria
• severe dehydration
• heart failure, pulmonary congestion, or renal dysfunction after initiation of mannitol

Question 8

What are the contraindications of loop diuretics?

Answer 8

• hypersensitivity to sulfonamides (contraindication for furosemide, bumetanide, and torsemide)
• anuria
• co-administration with amino glycosides increases ototoxicity and nephrotoxicity

Question 9

What are the contraindications of thiazide diuretics?

Answer 9

• anuria
• hypersensitivity to sulfonamides
• co-administration with agents that prolong QT interval

Question 10

What are the contraindications of collecting duct (potassium-sparing) diuretics?

Answer 10

• anuria
• hyperkalemia
• acute renal insufficiency