CMV

Question 1

Clinical presentation of CMV?

Answer 1

1. Congenital CMV Infection - mild sequelae
2. Cytomegalic inclusion disease (severe disease)
   - Intrauterine or perinatal infection
   - jandice, hepatosplenomegaly, thrombocytopenia, hemolytic anemia, interstitial pneumonitis
   - neurologic sequelae - microcephaly, chorionetrinitis, optic atrophy, mental retardation, spasticity, epilepsy
   - ‘owl eyes’
   - teratogenic
3. Post natal hepatitis
4. Infectious Mononucleosis Syndrome
   - glandular fever, mild hepatitis, atypical lymphocytes
5. Guillain Barre Syndrome

Question 2

Diagnosis of CMV

Answer 2

Virus Isolation (urine + throat swab into human cell culture) =