What is Polymixin E known as?
Colistin
What should be used for really resistant PEK bugs and SPACE bugs, the “kitchen sink”?
Colistin
Is Colistin Bacteriocidal or Bacteriostatic?
Bacteriocidal
What are the 2 common adverse reactions to Colistin?
Nephrotoxicity
Neurotoxicity
What unique routes of administration are there for Colistin?
Nebulization (Inhaled)
Intrathecal (rare)
In what form is Colistin administered?
Pro-drug format as
• Colistimethate sodium (IV)
What bugs are covered by Colistin?
-PAN-RESISTANT G– ORGANISMS