Fosfomycin (Monrol)

Question 1

Is Fosfomycin (Monrol) Bacteriocidal or Bacteriostatic?

Answer 1

Bacteriocidal

Question 2

When is the ONLY time Fosfomycin (Monrol) is used?

Why?

Answer 2

UTIs

low serum concentrations

Question 3

Why is Fosfomycin (Monrol) dosing so convenient?

Answer 3

3 gram PO once

Question 4

What bugs are covered by Fosfomycin (Monrol)?

Answer 4

MDR pathogens either G+ or G–

• MRSA
• VRE
• ESBL
• SPACE

Question 5

When wondering whether to use Fosfomycin (Monrol) what should you basically be thinking?

Answer 5

UTI ONLY

really resistant G+ or G–

Question 6

What adverse reaction is known to occur with Fosfomycin (monrol) usage?

Answer 6

GI upset