Complement Receptors

Question 1

CR1

Cells, ligand, function

Answer 1

• RBCs, phagocytes, granulocytes, B cells, some T cells
• C3b, C4b
• Elimination, immuncomplex transport and elimination

Question 2

CR2

Cells, ligand, function

Answer 2

• B cells, follicular DCs, some T cells
• C3d, C3dg, iC3b
• Activation of B cells

Question 3

CR3

Cells, ligand, function

Answer 3

• Phagocyte, NK cells, granulocytes
• iC3b, C3b, C3d
• phagocytosis, WBC-endothelium adhesion

Question 4

CR4

Cells, ligand, function

Answer 4

• B cells, T cells, NK cells
• iC3b, C3b
• Phagocytosis, adhesion