Congenital Abnormalities CPC

Question 1

Uterine tubes develop from the unfused portion of the paramesonephric ducts while the inferior portions fuse and form the ____

Answer 1

uterovaginal primordium

Question 2

Sinovaginal bulbs fuse to form the ___

Answer 2

vaginal plate

Question 3

Central cells of the vaginal plate degenerate to form the ____

Answer 3

lumen of the vagina

Question 4

The lumen is separated from the uterogenital sinus cavity by the ___

Answer 4

hymen

Question 5

MRKH

Answer 5

uterine and vaginal agenesis –> vertical defect

Question 6

Lateral fusion defects

Answer 6

uterus doesn’t come together properly –> e.g. didelphys

Question 7

T/F Lateral fusion defects are often associated with renal agenesis on the ipsilateral side

Answer 7

T

Question 8

Genes implicated in mullerian agenesis

Answer 8

wnt 4, hox, klippel feil syndrome association