oral bulk forming laxatives options
psyllium powder (metamucil)
methycellulose (citrucel)
polycarbophil (fiber con)
Inulin (Mirafiber)
oral bulk forming laxatives MOA
fiber absorbs water. as the fiber expands, pressure is increased on the intestine walls, and this promotes bowel movement (push on walls, walls push back)
oral bulk forming laxatives sx to be treated
PREVENTION of constipation or treatment for CHRONIC constipation
oral bulk forming laxatives is 1st line treatment when
rapid relief is not required and patient drinks adequate fluids daily
why are oral bulk forming laxatives not a good choice for acute constipation
slow onset of action
oral bulk forming laxatives SE
flatulence
abdominal bloating/ gas buildup
can oral bulk forming laxatives be used chronically YE
yes
T/F: oral bulk forming laxatives are safe for all populations
true
are oral bulk forming laxatives recommended for opioid induced constipation?
no
avoid oral bulk forming laxatives in patients with
dysphasia
difficulty swallowing
bedridden
cant drink adequate fluids
(fiber can swell in throat and can cause choking in not taken with full glass of fluid)
oral/ rectal stimulant laxative options
bisacodyl (dulcolax) (fleet bisacodyl)
senna (senaknot) (Exlax)
are oral/ rectal stimulant laxative mush or push
push
when is it a good idea to use rectal suppositories
patients with nausea and vomiting
oral/ rectal stimulant laxative MOA
stimulants irritate the GI mucosa, stimulating smooth contraction and secretion of water resulting in a bowel movement
why are oral/ rectal stimulant laxative last tine for pediatric pateints
gastric cramping
oral/ rectal stimulant laxative sx to be treated
TREATMENT of acute constipation
PREVENTION AND TREATMENT of acute and chronic opioid induced constipation
pre- procedural emptying
why do some opioids cause constipation
opioids decrease peristalsis
oral/ rectal stimulant laxative SE
GI cramping
rectal irritation (suppository: less preferred by patients)
T/F: diarrhea is technically a SE of any laxative
true
bisacodyl suppository on set of action
15- 60 min
senna and bisacodyl tablet onset of action
6- 10 hours
are oral/ rectal stimulant laxative pregnancy and lactation parameters
safe in pregnancy for short- term use, but not preferred because can be confused for contractions
senna can cause
discoloration of urine
bisacodyl patient counseling points
bisacodyl tablets are enteric coated, so they should not be taken with PPIs, H2RAs, or antacids as the acid reducers promote degradation of enteric coating, leading to dissolution in the stomach instead of intestines which prevents efficacy and causes gastric irritation or dyspepsia
patients should separate tablets from milk by 1 hour for the same reason