fever/ headache matrix Flashcards

(48 cards)

1
Q

acetaminophen brand name

A

tylenol

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2
Q

acetaminophen adult + pediatric dosing + max dose

A

adult: 325- 1000mg IR q4-6hr; 650- 1300mg ER q8hrs
Max: 4000mg/day

Pediatric: 10-15mg/kg q4-6hr
max: 5 doses in 24 hours

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3
Q

acetaminophen class + MOA

A

class: antipyretic, analgesic: central inhibition of prostaglandin synthesis (PGE2 for fever)

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4
Q

acetaminophen sx that will be treated

A

1st line therapy for fever discomfort
mild to moderate headache pain

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5
Q

acetaminophen onset of action

A

30 min- 1 hr with reduction in fever by 1-2 degrees
max temp reduction at 2 hours

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6
Q

acetaminophen side effects

A

none

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7
Q

acetaminophen pregnancy and breastfeeding parameters

A

safe

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8
Q

acetaminophen should be used in a lower dose (2g/day) in what populations (4)

A
  1. chronic liver disease
  2. concurrent use of hepatoxic drugs
  3. poor nutritional intake
  4. alcohol abuse
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9
Q

ibuprofen brand name

A

motrin, advil

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10
Q

ibuprofen adult + pediatric + max dose

A

adult: 200- 400mg q6-8hr
max: 1200mg/day

pediatric: 5- 10 mg/kg q6-8hr
max: 4 doses/24hrs

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11
Q

ibuprofen low dose vs. high dose

A

low: reduce pain/ fever
high: inflammation/ high fever

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12
Q

ibuprofen class + MOA

A

NSAID/ analgesic/ antipyretic/ anti- inflammatory: inhibits COX-1 and COX- 2 centrally and peripherally to reduce prostaglandin synthesis (PGE2 for fever)

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13
Q

ibuprofen sx that will be treated

A

1st line for fever discomfort (may be more effective than APAP)
mild to moderate headache pain

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14
Q

ibuprofen onset of action

A

30 min- 1hr with reductions in fever by 1-2 degrees. max temp reduction at 2 hours

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15
Q

ibuprofen side effects (7)

A
  1. upset stomach: counsel to take with food
  2. stomach ulcer/ bleeding
  3. bleeding
  4. decreased kidney function
  5. increased blood pressure
  6. worsening of heart failure/ fluid retention
  7. increased risk of MI
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16
Q

ibuprofen DI

A

warfarin, lithium, drugs that increase risk of bleednig

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17
Q

ibuprofen pregnancy and breastfeeding parameters

A

caution after 20 weeks, avoid after 30 weeks
avoid in breastfeeding

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18
Q

ibuprofen age restriction

A

> 6months

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19
Q

ibuprofen CI

A

patients with ASA allergy

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20
Q

ibuprofen caution in populations (5)

A
  1. CV disease
  2. high risk of cardiac events
  3. renal impairment
  4. heart failure
  5. edema
21
Q

Naproxen brand name

22
Q

Naproxen onset of action

23
Q

Naproxen age restirction

24
Q

Naproxen dosing + max

A

dosing: initial 440mg followed by 220mg q8-12hrs
max: 660mg/ day

25
Naproxen class + MOA
NSAID/ analgesic/ antipyretic/ anti- inflammatory: inhibits COX-1 and COX- 2 centrally and peripherally to reduce prostaglandin synthesis (PGE2 for fever)
26
Naproxen sx that will be treated
fever discomfort (best is patient needs relief for 8-12 hours) mild to moderate headache pain
27
Naproxen side effects (7)
1. upset stomach: counsel to take with food 2. stomach ulcer/ bleeding 3. bleeding 4. decreased kidney function 5. increased blood pressure 6. worsening of heart failure/ fluid retention 7. increased risk of MI
28
Naproxen DI
warfarin, lithium, drugs that increase the risk of bleeding
29
Naproxen pregnancy and breastfeeding parameters
caution after 20 weeks, avoid after 30 weeks avoid in breastfeeding
30
Naproxen CI
patients with ASA allergy
31
Naproxen caution in population (5)
1. CV disease 2. high risk of cardiac events 3. renal impairment 4. heart failure 5. edema
32
Aspirin brand name
ecotrin, bayer
33
Aspirin dose for CV protection and pain, fever, inflammation + max dose
CV protection: 81mg pain, fever, inflammation: 325- 1000mg max: 4000mg/day
34
Aspirin age restriction
>15yrs
35
why is Aspirin CI in ages <15yrs
risk of reyes syndrome
36
Aspirin class + MOA
NSAID/ analgesic/ antipyretic/ anti- inflammatory: inhibits COX-1 and COX- 2 centrally and peripherally to reduce prostaglandin synthesis (PGE2 for fever) for CV protection: irreversible platelet effects
37
Aspirin sx that will be treated
fever discomfort in adults (NOT GOOD CHOICE) mild to moderate headache pain (generally not used for headache)
38
Aspirin side effects (6)
1. upset stomach, heartburn 2. stomach ulcer/ bleeding 3. bleeding 4. decreased kidney function 5. increased blood pressure 6. worsening of heart failure/ fluid retention (increased risk of side effects in elderly patients)
39
Aspirin pregnancy + breastfeeding parameters
CI
40
Aspirin caution in populations (2)
1. asthmatics 2. ASA allergy
41
what is in the combo product exedrine
asa, apap, caffeine
42
exedrine sx that will be treated
mild to moderate headache pain, migraine headache
43
what is in the combo product advil/ tylenol cold and sinus
NSAID or APAP + decongestant (pseudoephedrine or phenylephrine)
44
recommend for flu/ COVID testing (9)
fever/ chills + 1. cough 2. SOB/ difficulty breathing 3. sore throat 4. congestion/ runny nose 5. new loss of taste or smell 6. fatigue 7. muscle or body aches 8. headache 9. N/V
44
advil/ tylenol sx that will be treated
mild to moderate headache pain, sinus headache
45
high risk patients needing referral if positive for flu/ COVID- 19 (5)
1. >65 yrs 2. <6months or <5yrs with comorbities (asthma, immune dysfunction, prematurity) 3. weakened immune system 4. disabilities 5. pregnancy
46
automatic referral for emergency medical attention w/ COVID- 19 or flu (5)
1. trouble breathing 2. persistent pain or pressure in chest 3. new confusion 4. inability to wake to stay awake 5. skin appears pale, gray or blue
47
referral criteria if COVID/ flu is negative (11)
1. fever that persists >72hrs 2. <3 months this temp of >100.4 without other sx 3. temp >104 without other sx 4. fever + excessive heat exposure 5. fever + history of pulm disease + COPD 6. fever + impaired immune function 7. fever + CNS damage 8. fever + history of febrile seizures 9. fever + child refusing to drink 10. fever + child who is very sleepy/ irritable/ hard to wake up 11. fever + child has a stiff neck