Deck1 Flashcards

(53 cards)

1
Q

What is the primary goal of oncology pharmacology?

A

To develop and use drugs for the treatment of cancer.

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2
Q

True or False: Chemotherapy is the only treatment modality in oncology.

A

False

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3
Q

Fill in the blank: The primary class of drugs used in chemotherapy are __________.

A

cytotoxic agents

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4
Q

What does the term ‘targeted therapy’ refer to in oncology?

A

Drugs that specifically target cancer cell mechanisms.

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5
Q

Which of the following is a common side effect of chemotherapy? A) Hair loss B) Increased energy C) Weight gain

A

A) Hair loss

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6
Q

What is the mechanism of action of alkylating agents?

A

They bind to DNA and prevent replication.

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7
Q

True or False: Immunotherapy enhances the body’s immune response against cancer cells.

A

True

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8
Q

Name one common class of drugs used in hormone therapy for cancer.

A

Aromatase inhibitors

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9
Q

What does the acronym ‘HER2’ stand for?

A

Human Epidermal growth factor Receptor 2

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10
Q

Fill in the blank: __________ is the process of using drugs to shrink tumors before surgery.

A

Neoadjuvant therapy

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11
Q

Which type of cancer is often treated with platinum-based drugs?

A

Ovarian cancer

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12
Q

What is the role of monoclonal antibodies in cancer treatment?

A

To specifically target and inhibit cancer cell growth.

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13
Q

True or False: All chemotherapy agents are administered intravenously.

A

False

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14
Q

What is the significance of the ‘5-year survival rate’ in oncology?

A

It indicates the percentage of patients who live at least five years after diagnosis.

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15
Q

Name one side effect associated with targeted therapies.

A

Skin rash

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16
Q

What is the purpose of radiation therapy in oncology?

A

To kill cancer cells and shrink tumors using high-energy radiation.

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17
Q

Which drug is commonly used as a first-line treatment for breast cancer?

A

Tamoxifen

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18
Q

Fill in the blank: __________ therapy uses the body’s own immune system to fight cancer.

A

Immunotherapy

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19
Q

What is the main advantage of using combination chemotherapy?

A

To increase the effectiveness of treatment and reduce resistance.

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20
Q

True or False: Cancer cells can develop resistance to chemotherapy drugs.

A

True

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21
Q

What is the standard treatment for localized prostate cancer?

A

Surgery or radiation therapy

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22
Q

Which medication is an example of an anti-angiogenic drug?

23
Q

Fill in the blank: __________ is the term for the study of the effects of drugs on cancer patients.

A

Oncology pharmacology

24
Q

What is the purpose of dose adjustment in chemotherapy?

A

To minimize toxicity and maximize therapeutic effect.

25
True or False: All patients respond the same way to cancer treatments.
False
26
What does the term 'palliative care' mean in oncology?
Care aimed at providing relief from symptoms and improving quality of life.
27
What is the primary use of chemotherapy in oncology?
To kill or inhibit the growth of cancer cells.
28
True or False: All chemotherapy drugs have the same side effects.
False
29
Name one common side effect of doxorubicin.
Cardiotoxicity
30
What is the mechanism of action of alkylating agents?
They damage DNA by adding alkyl groups to DNA strands.
31
Fill in the blank: Cisplatin is contraindicated in patients with ________ impairment.
renal
32
Which drug is known for causing peripheral neuropathy?
Vincristine
33
What is a common side effect associated with taxanes?
Hypersensitivity reactions
34
True or False: Methotrexate is used as a first-line treatment for breast cancer.
False
35
What type of drug is trastuzumab?
Monoclonal antibody
36
What is a significant side effect of cyclophosphamide?
Hemorrhagic cystitis
37
Which class of drugs does pemetrexed belong to?
Antimetabolites
38
Name one contraindication for the use of paclitaxel.
Severe hypersensitivity to taxanes
39
What is the primary side effect of irinotecan?
Diarrhea
40
Fill in the blank: Bevacizumab is contraindicated in patients with ________ disorders.
hemorrhagic
41
True or False: All patients can receive chemotherapy without any adjustments.
False
42
What is the risk associated with using gemcitabine?
Pulmonary toxicity
43
Which drug is used in the treatment of HER2-positive breast cancer?
Trastuzumab
44
What is an important consideration when administering doxorubicin?
Monitoring for signs of heart failure.
45
What type of cancer is commonly treated with imatinib?
Chronic myeloid leukemia (CML)
46
Fill in the blank: The side effect of ________ is associated with methotrexate.
mucositis
47
True or False: Patients receiving chemotherapy should not be monitored for blood counts.
False
48
What is the primary mechanism of action for antimetabolites?
They interfere with DNA and RNA synthesis.
49
Name one drug that is a platinum-based chemotherapy agent.
Cisplatin
50
Which chemotherapy agent is known to cause nail changes?
Docetaxel
51
Fill in the blank: ________ is a common side effect of 5-fluorouracil.
Stomatitis
52
What should be monitored when a patient is on doxorubicin?
Ejection fraction
53
True or False: Hormonal therapies are considered chemotherapy.
False