1
Q
- absence of melanocytes
* causes depigmentation
A
Vitiligo
2
Q
- associated with defects in collagen support structure of dermis
A
Ehlers-Danlos Syndrome
3
Q
- location: flexor surfaces in adults
- etiology: filaggrin mutation
- associated with asthma and allergic rhinitis
- staph aureus is suggested to exacerbate this disorder
- in children, is on cheecks and extensor surfaces
- eczema is type of atopic dermatitis
A
Atopic Dermatitis
4
Q
- type of atopic dermatitis
A
Eczema
5
Q
- etiology: common irritants
A
Irritant Contact Dermatitis
6
Q
- etiology: common allergens
- delayed type hypersensitiviey reaction (type 4)
- diagnosis confirmed with patch testing
- skin biopsy would reveal spongiotic dermatitis
A
Contact Dermatitis
7
Q
- location: lower legs
* etiology: lower extremity edema
A
Stasis Dermatitis
8
Q
- same as nummular eczema
- round, annular, scaly plaques
- due to dry skin
- overuse of soap can make this worse
A
Numular Dermatitis
9
Q
- location: scalp
- etiology: malassezia furfur
- also known as cradle cap
- infection of sebaceous glands
A
Seborrheic Dermatitis
10
Q
- location: extensor surfaces
- may include arthritis
- may be associated with increased cardiovascular risk
A
Chronic Plaque Psoriasis
11
Q
- skin cancer
- most common
- pearly
- common on nose
- tx: mohs surgery, vismoedgib (blocks smoothend gene)
A
Basal Cell
12
Q
- second most common skin cancer
- occurs more common in immunosupporessed pts keratoacanthoma is a type of this cancer
- center crater
- develop rapidly
- on sunexposed skin, HPV, thermal injury
- actinic keratosis is premalignant skin lesion
A
Squamous Cell
13
Q
- skin cancer
A
Melanoma
14
Q
- often associated with immunodeficiency
A
Kaposi Sarcome
15
Q
- can be treated with beta blockers
- most common benign soft tissue tumor of infants
- GLUT1 positive
A
Infantile Hemangioma
16
Q
- associated with high levels of GLUT-1 expression (a placenta associated marker)
- also called strawberry hemangioma
A
Infantile Hemangioma
17
Q
- associated with glaucoma and seizures
A
Port Wine Stain
18
Q
- linear plaque on the face or scalp
- yellow-orange
- associated with allopecia
A
Nevus Sebaceus
19
Q
- most commonly on face>trunk>extremity
* beign tumor of oil gland
A
Sebaceus Hyperplasia
20
Q
- from fibroblast
- firm papule
- most common on legs
- dimple sign is characteristic
A
Dermatofibroma
21
Q
- scar gowth above and beyond original border
A
Keloid Scar
22
Q
- sudden appearance associated with adenocarcinoma of the stomach
A
Seborrheic Karatosis
23
Q
- flat macules
* palms and soles most common
A
Junctional Nevus
24
Q
- more common in asians and causcasians
A
Blue Nevus
25
* biggest risk factor for melanoma
* familial atypical moles and melanoma criteria: The occurrence of malignant melanoma in 1 or more first- or second-degree relatives The presence of numerous (often >50) melanocytic nevi, some of which are clinically atypical Many of the associated nevi showing certain histologic features CDK2NA mapped to 9p21 CDK4 mapped to 12q14 CMM1 mapped to 1p
FAMMM Syndrome
26
* six or more cafe au lait spots
* two or more neurofibromas
* axillary or inguinal freckling (Crowe's sign)
* first degree relative with disorder
* autosomal dominant
Neurofibromatosis
27
* multiple lesions associated with neurofibromatosis
Cafe au Lait Patch
28
* melassezia furfur is causative agent
Tinea Versicolor
29
* acquired disease involving antibodies to cell-to-cell adhesion molecules in the stratum spinosum (keratinocytes)
* attacks desmosomes
Permphigus Vulgaris
30
* vitamin cross links tropocollagen together
* this disease is characterized by lack of vitamin C
* SS: keratotic plugging of hairs, corkscrew hairs, hemorrhagic gingivitis
Scurvy
31
* type 2 antibody mediated
| * detachment between dermis and epidermis- hemidesomsomes
Bullous Pemphigoid
32
* do not debride
| * tx with steroids and immunosuppression
Pyoderma Gangrenosum
33
* associated with hepatitis
Lichen Planus
34
* with internal malignancies, pts tend to have weight loss- most common is stomach cancer
* thickening of the skin
* common causes: obesity, diabetes
Acanthosis Nigricans
35
* filagrin mutation
Icthyosis Vulgaris
36
* honey colored
| * associated with strep and staph
Impetigo
