DEET

Question 1

What is a common use of DEET?

Answer 1

Insect repellant

Question 2

What is the Acute oral LD50 in rats for DEET?

Answer 2

2g/kg

Question 3

What is the acute dermal LD50 in rabbits for DEET?

Answer 3

3g/kg

Question 4

DEET toxicokinetics

Answer 4

Absorbed through the skin
can increase dermal absorption of other products
Metabolized inthe liver and excreted in urine

Question 5

What are the clinical signs of DEET?

Answer 5

Rats and Rabbits: 
Depression 
excitation 
ataxia 
tremors
seizures 
coma

Dogs and Cats: 
Salivation
Vomiting 
hyperexcitability 
tremors
ataxia 
seizures

Question 6

What should chemical analysis be used on to detect DEET?

Answer 6

stomach contents
urine 
blood 
skin 
vitreous humor 
bile 
kidney

Question 7

What is considered diagnostic for DEET?

Answer 7

20ppm
Urine concentrations greater than 1ppm
tissue greater than 10ppm

Question 8

Treatment for DEET?

Answer 8

No specific antidote
Decontamination: Emesis, Activated Charcoal
Symptomatic treatment

Question 9

What is the prognosis for DEET?

Answer 9

Good - respond in 24-72hours