depression

Question 1

citalopram dose

Answer 1

max 40 mg/day; max dose in >60 yo 20 mg/day

Question 2

escitalopram

Answer 2

max dose 20 mg/day; max dose in elderly 10 mg/day

Question 3

Symbyax

Answer 3

fluoxetine + olanzapine (dosed QHS)

Question 4

Brisdelle

Answer 4

paroxetine for vasomotor sx (CI in pregnancy)

Question 5

approved for PMDD

Answer 5

fluoxetine, Paxil CR, sertraline

Question 6

Marplan

Answer 6

isocarboxazid

Question 7

Nardil

Answer 7

phenelzine

Question 8

Parnate

Answer 8

tranylcypromine

Question 9

Effexor XR

Answer 9

venlafaxine

Question 10

max dose of venlafaxine

Answer 10

375 mg/day (IR)

Question 11

increased NE side effects

Answer 11

dilated pupils, sweating, constipation, inc BP, dry mouth

Question 12

Doxepin

Answer 12

amitriptyline (secondary amine)

Question 13

Pamelor

Answer 13

nortriptyline (tertiary amine)

Question 14

Silenor

Answer 14

amitriptyline for insomnia

Question 15

take with food

Answer 15

vilazodone

Question 16

buproprion moa

Answer 16

DA and NE reuptake inhibitor

Question 17

buproprion dose

Answer 17

don’t exceed 450 mg/day (seizure risk)

Question 18

Emsam

Answer 18

selegiline patch (MAO-B selective inhibitor)

Question 19

Remeron

Answer 19

mirtazepine

Question 20

natural products that inc serotonin

Answer 20

st john’s wort, 5-HTP, SAMe

Question 21

SSRI use in pregnancy

Answer 21

escitalopram, sertraline

Question 22

activating antidepressants

Answer 22

fluoxetine, buproprion

Question 23

low risk of sexual dysfunction

Answer 23

mirtazepine, buproprion

Question 24

priapism

Answer 24

trazodone

Question 25

nefazodone

Answer 25

bbw hepatotoxicity (rarely used)

Question 26

QT prolongation

Answer 26

citalopram, escitalopram, venlafaxine, TCAs, mirtazepine, trazodone

Question 27

SIADH/hyponatremia, fall risk

Answer 27

SSRIs, SNRIs

Question 28

orthostasis, fall risk

Answer 28

TCAs