Development 1 Flashcards

(60 cards)

1
Q

Female internal genital organs include

A

Fallopian tubes, uterus, cervix, upper one-third of vagina

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2
Q

Embryological duct for female internal genitalia

A

Müllerian (paramesonephric) ducts

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3
Q

Week of appearance of Müllerian ducts

A

6th week of intrauterine life

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4
Q

Hormonal requirement for female differentiation

A

Absence of AMH and testosterone

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5
Q

Fate of Müllerian ducts in females

A

Persist and differentiate

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6
Q

Fate of Wolffian ducts in females

A

Regress

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7
Q

Reason for Wolffian duct regression

A

Absence of testosterone

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8
Q

Cranial unfused Müllerian ducts form

A

Fallopian tubes

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9
Q

Caudal fused Müllerian ducts form

A

Uterus and cervix

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10
Q

Upper one-third of vagina develops from

A

Müllerian ducts

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11
Q

Lower two-thirds of vagina develops from

A

Urogenital sinus

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12
Q

Direction of Müllerian duct growth

A

Cranio-caudal

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13
Q

Direction of Müllerian duct fusion

A

Caudal to cranial

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14
Q

Name of fusion between Müllerian ducts

A

Lateral fusion

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15
Q

Structure formed after fusion

A

Uterovaginal canal

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16
Q

Process following fusion

A

Resorption of central septum

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17
Q

Failure of septal resorption causes

A

Septate uterus

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18
Q

Failure of lateral fusion causes

A

Bicornuate uterus

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19
Q

Complete failure of fusion causes

A

Uterine didelphys

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20
Q

Partial failure of fusion causes

A

Bicornuate uterus

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21
Q

Failure of Müllerian duct development

A

Müllerian agenesis

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22
Q

Another name for Müllerian agenesis

A

MRKH syndrome

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23
Q

Uterus in MRKH syndrome

A

Absent

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24
Q

Ovaries in MRKH syndrome

A

Normal

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25
Secondary sexual characters in MRKH
Normal
26
Most common Müllerian anomaly
Septate uterus
27
Anomaly with best reproductive outcome
Arcuate uterus
28
Shape of arcuate uterus
Mild fundal indentation
29
Embryological origin of cervix
Fused Müllerian ducts
30
Blood supply relevance in anomalies
Affects pregnancy outcome
31
Sinovaginal bulbs arise from
Urogenital sinus
32
Fusion of sinovaginal bulbs forms
Vaginal plate
33
Canalization of vaginal plate forms
Vaginal lumen
34
Failure of vaginal plate canalization
Vaginal atresia
35
Embryological origin of hymen
Urogenital sinus
36
Cause of imperforate hymen
Failure of hymenal canalization
37
Condition caused by imperforate hymen
Hematocolpos
38
Ovarian embryological origin
Genital ridge
39
Are ovaries Müllerian derivatives?
No
40
Origin of primordial germ cells
Yolk sac
41
Time of germ cell migration
By 6th week
42
Commonly associated anomalies with Müllerian defects
Renal anomalies
43
Most common renal anomaly
Unilateral renal agenesis
44
Side commonly affected in renal anomaly
Right
45
Another system associated with Müllerian anomalies
Skeletal system
46
Vertebral anomalies seen in
MRKH syndrome
47
Imaging modality of choice for uterine anomalies
MRI pelvis
48
Initial screening investigation
Ultrasound pelvis
49
Gold standard for classification of uterine anomalies
MRI
50
ASRM classification is based on
Embryological defect
51
Complication of septate uterus
Recurrent pregnancy loss
52
Complication of bicornuate uterus
Preterm labor
53
Characteristic feature of uterine didelphys
Double cervix
54
Cervical duplication seen in
Uterine didelphys
55
Vaginal septum is associated with
Fusion defects
56
Cause of transverse vaginal septum
Failure of vertical fusion
57
Vertical fusion occurs between
Müllerian duct and urogenital sinus
58
Failure of vertical fusion leads to
Transverse vaginal septum
59
Clinical importance of genital tract development defects
Infertility, RPL, obstetric complications
60
Most important exam correlation in Müllerian anomalies
Always evaluate kidneys