Dextrose

Question 1

Dextrose Class:

Answer 1

Carbohydrate, hypertonic solution

Question 2

Dextrose Mechanism of Action:

Answer 2

Rapidly increases serum glucose levels

Short-term osmotic diuresis

Question 3

Dextrose Indications:

Answer 3

Hypoglycemia
Altered level of consciousness
Coma of unknown etiology
Seizure of unknown etiology
Status epilepticus (controversial)

Question 4

Dextrose Contraindications:

Answer 4

Intracranial hemorrhage
Delirium tremens
Ineffective without thiamine

Question 5

Dextrose Adverse Reactions:

Answer 5

Extravagation leads to tissue necrosis
Warmth
Pain
Burning
Thrombophlebitis
Rhabdomyositis

Question 6

Dextrose Drug Interactions:

Answer 6

Sodium bicarbonate

Coumadin

Question 7

Dextrose How Supplied:

Answer 7

25 gm/ 50 ml pre-filled syringes (500 mg/ml)

Question 8

Dextrose Dosage and Administration:

Answer 8

Adult:

12. 5-25 gram slow IV; may be repeated as necessary Pediatric:
13. 5-1 gm/kg/dose slow IV; may be repeated as necessary

Question 9

Dextrose Onset:

Answer 9

Less than 1 minute

Question 10

Dextrose Peak Effect:

Answer 10

Variable

Question 11

Dextrose Duration:

Answer 11

Variable

Question 12

Dextrose Special Considerations:

Answer 12

• Administer thiamine prior to D50 in known alcoholic patients
• Draw blood sugar before administering
• Do not administer to patients with known CVA unless hypoglycemia documented