Furosemide

Question 1

Furosemide: Class

Answer 1

Loop Diuretic

Question 2

Furosemide: Mechanism of Action

Answer 2

Inhibits electrolyte reabsorption and promotes excretion of sodium, potassium, chloride.

Question 3

Furosemide: Indications

Answer 3

CHF
Pulmonary Edema
Hypertensive Crisis

Question 4

Furosemide: Contraindications

Answer 4

Hypovolemia
Anuria
Hypotension (relative contraindication)
Hypersensitivity
Hepatic Coma

Question 5

Furosemide: Adverse Reactions

Answer 5

May exacerbate Hypovolemia
Hypokalemia
Hypochloremia
Hyponatremia 
Hyperglycemia (due to hemoconcentration)
ECG changes
Dry mouth

Question 6

Furosemide: Drug Interactions

Answer 6

• Lithium toxicity may be potentated by sodium depletion.

- Digitalis toxicity may be potentated by potassium depletion.

Question 7

Furosemide: How Supplied

Answer 7

100 mg / 5 ml
20 mg / 2 ml
40 mg / 4 ml vials

Question 8

Furosemide: Dosage and Administration

Answer 8

Adult: 0.5-1mg/kg slow IV push
Pediatric: 1 mg / kg / dose IV, IO.

Question 9

Furosemide: Onset

Answer 9

5 Minutes

Question 10

Furosemide: Peak Effect

Answer 10

20-60 Minutes

Question 11

Furosemide: Duration

Answer 11

4-6 Hours

Question 12

Furosemide: Pregnancy Class

Answer 12

C

Question 13

Furosemide: Special Considerations

Answer 13

• Ototoxicity and deafness can occur with rapid administration.
• Should be protected from light.