Dextrose

Question 1

Drug Classification

Answer 1

Carbohydrate

Question 2

Mechanism of Action

Answer 2

Raises blood glucose simply by added presence directly into vasculature

Question 3

Pharmacokinetics

Answer 3

Onset of Action- <1 minute
Peak Effects- varies
Duration of Effects- varies
Half-Life- N/a

Question 4

Indications/Field Use

Answer 4

• Hypoglycemia

- Hypoglycemia during neonatal resuscitation (D10 only)

Question 5

Contraindications

Answer 5

Hyperglycemia

Question 6

Side Effects/Adverse Reactions

Answer 6

-tissue necrosis/phlebitis at injection site

Question 7

Dose

Answer 7

Adult:
25g slow IV/IO (D10 or D50) or until dose administered yields appropriate mental status

Pedi:
0.5-1g/kg slow IV/IO (D10 or D25)

Question 8

Precautions

Answer 8

• Local venous irritation may occur in smaller veins
• Caution with pt’s with increased ICP or cerebral edema
• D50 should not be used in pt’s younger than 16, but may be diluted 1:1 with sterile water to make D25 for children

Question 9

Drug-Drug Interaction

Answer 9

None Ems