Digoxin

Question 1

Drug Class

Answer 1

Antiarrhythmics

Question 2

Active

Answer 2

Digoxin

Question 3

Indications

Answer 3

• AF and atrial flutters

- HF

Question 4

Dose Range

Answer 4

D(loading) = 250 – 500mcg every 4-6 hours (m=1.5mg)

D(maintenance) = 125 – 250 mcg once daily

*halve doses in renally impaired

Question 5

SE’s

Answer 5

• anorexia
• n/v
• diarrhoea
• blurred vision
• drowsiness

thrombocytopenia, seizures, confusion, psychosis, gynaecomastia (RARE)

Question 6

Counselling

Answer 6

Label: 5

• Tell your doctor or pharmacist that you are taking digoxin before using any other medicines, including OTC medications
• be aware of signs of toxicity
  • anorexia
  • n/v
  • visual disturbances (blurred vision, yellow vision)
• Risk of digoxin toxicity is increased by conditions/medications causing hypokalaemia, hypomagnesaemia, hypercalcaemia, acidosis, hypoxia.

Question 7

Monitoring

Answer 7

• Renal function
• Electrolyte concentration
• digoxin concentration (alter dose if required)
• resting heart rate