Diphenhydramine

Question 1

Generic Name

Answer 1

Diphenhydramine

Question 2

Trade Name

Answer 2

Benadryl

Question 3

Class

Answer 3

Antihistamine

Question 4

Action

Answer 4

Blocks histamines at h1 receptor sites inhibiting actions of histamine release, reverses dystonic reactions and extrapyramidal symptoms (involuntary movement disorders)

Question 5

Indications

Answer 5

Mild to moderate allergic reactions, anaphylaxis (give after administering epinephrine), dystonic reactions and other extrapyramidal symptoms

Question 6

Diphenhydramine Contraindications

Answer 6

Hypersensitivity MAOI’s neonates

Question 7

Adult Dose:

Answer 7

25–50 mg iV at 25 mg/min, repeated PRN

Question 8

Pedi Dose:

Answer 8

1–2 mg/kg iV (iM not recommended)

Question 9

Side Effects

Answer 9

Confusion Dizziness Drowsiness Dry Mouth Nausea Palpitations Tachycardia Vomiting

Question 10

Onset

Answer 10

15-30 min

Question 11

Duration

Answer 11

3-12 hrs