Maurice Wilson and Rosalind Franklin
conducted xray crystallography studies of DNA and proteins, couldn’t figure out whether DNA or proteins carried genetic info
James Watson and Francis Crick
won Nobel Prize for structure of DNA
Structure of DNA
width of DNA double helix
2.0 nm
distance between bases
0.34 nm
length of 1 complete turn of the helix
3-4 nm
DNA nucleotide consist of
phosphate group, deoxyribose sugar, nitrogenous base (1 of 4)
Thymine (T)
Adenine (A)
Cytosine (C)
Guanine (G)
5’ end
phosphate group
3’ end
hydroxyl group
the two strands of a DNA molecule are…
antiparallel