Nucleic Acids
The macromolecule that holds our genetic material
Genes
Sections of DNA that serve as blueprint/instructions for making protien
DNA
Deoxyribonucleic acid
Its sugar is deoxyribose
Its nitrogen base is made of Adenine Guanine Cytosine and Thymine
RNA
Ribonucleic acid
Its sugar is ribose
Its nitrogen base is made of Adenine Guanine Cytosine and Uracil (U replaces T)
Nucleotides
The monomer of nucleic acids
Has three parts
Sugar
Phosphate
Nitrogen Base
Double Helix Structure
Like a twisted ladder
Sugar and phosphate form the “sugar phosphate backbone”
Nitrogen bases bond in the middle with weak hydrogen bonds
All other bonds are covalent
RNA structure
A single strand of nucleotides with exposed bases
RNA bases bind with DNA bases
A bunds with U
C binds with G
Chromosomes
Tightly coiled strands of DNA
Different organisms have different numbers of chromosomes
(humans have 23 pairs, dogs have 37 pairs)
DNA replication
The process of making an identical copy of DNA
Must be done before a cell starts to divide
Happens in the Nucleus during the cell phase of interphase
Steps of DNA replication
Polymerase replicating the DNA with DNA
DNA Polymerase
Replicates DNA molecules (builds the new strand)
Helicase
Unzips the DNA
Primase
Makes the primer so DNA polymerase con figure out where to go
Ligase
Glues Okazaki fragments together
SSB protein
Single Stranded binding protein
it stops the DNA from coming back together during replication
Okazaki Fragment