Primary hormone regulating water balance
Arginine vasopressin (ADH)
Site of ADH production
Hypothalamic supraoptic and paraventricular nuclei
Central diabetes insipidus mechanism
Deficient ADH production or release
Nephrogenic diabetes insipidus mechanism
Renal resistance to ADH
Key diagnostic test for DI
Modified water deprivation test, serum osmolity
Treatment for central DI
Desmopressin acetate (DDAVP)
Urine osmolality in untreated DI
<300 mOsm/kg (hyposthenuric)
Primary hormone excess in acromegaly
Growth hormone
Common cause of feline acromegaly
Functional pituitary adenoma
Key diagnostic hormone for acromegaly
IGF-1
Clinical sign linked to GH excess
Insulin resistance
Definitive treatment option for acromegaly
Hypophysectomy or radiation therapy
Most common cause of canine hypothyroidism
Lymphocytic thyroiditis
Primary screening test for hypothyroidism
Total T4
Confirmatory test for hypothyroidism for dogs
Free T4 by equilibrium dialysis
Gold standard treatment for hypothyroidism
Levothyroxine
Classic lab abnormality of hypothyroidism
Hypercholesterolemia
Primary hormone elevated of hyperthyroidism
Thyroxine (T4)
Most common cause of hyperthyroidism
Adenomatous hyperplasia
Definitive treatment for hyperthyroidism
Radioiodine therapy (I-131)
Initial diagnostic test for hyperthyroidism
Serum total T4
Common complication of hyperthyroid treatment
Unmasking of chronic kidney disease
Most canine thyroid tumors type
Non-functional carcinomas
Primary diagnostic imaging for canine thyroid tumors
Cervical ultrasound and CT