Endocrine LAB

Question 1

Are different methods of glucometers more accurate than others? Why?
(Such as: vet glucometers vs human glucometers, or vs Catalyst)

Answer 1

Yes, different monitors are programmed/calibrated for different species

Question 2

What is the additive to a grey top tube?

Answer 2

Potassium oxalate/sodium fluoride

Question 3

What does the additive in grey top (K+ oxalate/Na+ fluoride) tube do to the blood sample?

Answer 3

Prevent clotting & preserve glucose levels in the sample

Question 4

What are the three main components of Continuous Glucose Monitors (CGM)?

Answer 4

1. Flexible, electroenzymatic, polyurethane membrane probe that is inserted via an introducer device thru the patient’s skin into the interstitial space (SQ).
2. Small sensor, attached to the probe, that adheres to the surface of the patient’s skin.
3. Handheld monitor, which may be a dedicated reader or smart phone.

Question 5

How to apply a continuous glucose monitor: (6)

Answer 5

1. Gather materials: clippers, alcohol wipes, sensor, gloves, & medical adhesive.
2. Select application site. Should be somewhere out of reach of patient and limited SQ movement.
3. Shave & clean area with alcohol. Allow to air dry.
4. Medical glue can be applied in a half donut formation on monitor.
5. Check sensor & applicator device lot numbers and expiration dates.
6. Apply firmly to patient until “click” is heard. Continue firm pressure for additional 10-20 seconds. Gentle remove application device.

Question 6

Advantages of continuous glucose monitor (3)

Answer 6

1. Consistency & comfort
   - Can eliminate the need for in-house glucose curves performed with multiple BD or ear pricks.
2. Enhanced data collection
   - Have been used to detect clinically relevant hypo-/hyperglycemic episodes.
   - Collect data at times that were not previously feasible.
3. Fewer resources needed & staff involvement.

Question 7

Disadvantages of continuous glucose monitors (5)

Answer 7

1. Even with correct placement, 10-25% of sensors don’t work.
2. Patient or sensor movement; limited SQ space or thin Pt; adhesive failure; bleeding; site infection can affect sensor.
3. Patient attempts to remove
4. Cost is about $100/sensor
5. Short function time in vet patients.
   - Designed to last 10-14 days in humans, 5-7 days of function is more common in veterinary patients.