Endocrine glands produce
hormones
Endocrine gland’s hormones are released into the
blood steam where they will reach target cells
Exocrine glands produce
non-hormonal substances
The non-hormonal substances from exocrine glands are released
onto body surface or into body cavity via ducts
What are the 4 general functions of the endocrine system
Too much hormone is secreted
Hypersecretion
Too little hormone is secreted
Hyposecretion
Most hormone secretion is controlled by
negative feedback
Hormone release is regulated by
reflexes to stimuli
What 3 types of stimuli initiate hormone release
Hormonal stimuli
release of hormone stimulates a gland to release another hormone
Humoral stimuli
changes in the blood stimulate hormone release
Nervous stimuli
nervous system directly stimulates hormone release
What are the 2 categories of hormones based on chemical make-up
What are 2 steroid-based hormones
What are 2 protein/amino acid-based hormones
Steroid/ lipid-soluble hormone can ______ ______ target cells
directly enter
Where are receptors located for steroid/lipid soluble hormone to bind to
inside the cell
Non-steroid/ water-soluble hormone can ____ _____ ________ target cells
not directly enter
Where are receptors located for non-steroid/ water-soluble hormone
outside the cell
Binding to receptors for non-steroid hormone activates
“second messenger” inside cell
A target cell’s response depends on what 2 things
Up-regulation _____ the number of receptors
increases
Up-regulation occurs when hormone levels are
low