What are endocrine glands?
They are comprised of tissue and secrete a substance or substances. In particular, they secrete hormones into the blood through extracellular fluid (bloodstream).
What are the effects of hormones?
These tend to be long-lasting, and are involved in the process of growth, sexual development and control of cell metabolism
Communication within the body involves…
…hormones.
What are target cells?
The specialised cells on which hormones act. The membranes of these cells consist of specific protein receptor molecules. These receptors detect the presence of hormones outside the cell, and carry the message across the cell through a series of enzyme reactions.
What is the pituitary gland?
It releases a variety of hormones that either have a direct effect, or cause other endocrine glands to release their specific hormones. It allows feedback to control the release of a hormone (e.g., TSH/Thyroxine model).
What are the types of hormones?
They can be either proteins or steroids (a type of lipid).
Describe steroid hormones.
They are lipid soluble (cholesterol) and are able to pass through the cell and nuclear membrane, directly affecting receptor molecules within the cell.
Describe protein hormones.
They are unable to pass through membranes, and they bind with protein receptors on the cell membrane.
Describe the location of endocrine glands throughout the body.
Brain: pituitary, hypothalamus and pineal
Neck: thyroid
Abdomen: adrenal and pancreas
Pelvis: female gonads (ovaries)
Scrotum: male gonads (testes)
Describe the hormone oxytocin.
Located in: pituitary
Action(s): uterine contractions during childbirth
Describe the hormone antidiuretic (ADH)
Located in: pituitary
Action(s): reabsorption of water in the kidneys
Describe the growth hormone (GH).
Located in: pituitary
Action(s): growth of body cells and tissues
Describe the follicle stimulating hormone (FSH).
Located in: pituitary
Action(s): stimulates ovaries and testes
Describe the luteinising hormone (LH).
Located in: pituitary
Action(s): stimulates ovulation in females and the release of testosterone in males
Describe the thyroid-stimulating hormone.
Located in: pituitary
Action(s): stimulates the activity of the thyroid gland
Describe the thyroxine hormone.
Located in: thyroid
Action(s): stimulates metabolism and heat production
Describe the parathyroid hormone (PTH).
Located in: parathyroid
Action(s): stimulates release of calcium from bone
Describe the hormone insulin.
Located in: pancreas
Action(s): lowers blood sugar
Describe the hormone glucagon.
Located in: pancreas
Action(s): raises blood sugar
Describe the hormone adrenalin.
Located in: adrenal
Action(s): increases blood sugar and constricts blood vessels
Describe the hormone testosterone.
Located in: testes
Action(s): male characteristics and controls sperm production
Describe the hormones oestrogen and progesterone.
Located in: ovaries
Action(s): female secondary sexual characteristics; maintain uterine lining
Describe the hormone thymosin.
Located in: thymus
Action(s): stimulates production of lymphocytes
How are hormone levels maintained?
By a negative feedback system, where negative feedback is a mechanism that maintains the balance of supply and demand between hormone levels and the needs of target cells. This involves the response reversing the stimulus.