negative feedback
hormone inhibits its own release
down-regulation of receptors
a hormone decreases the affinity and number of its receptors
hormonal or neural mechanisms
hormones are transported in the blood and interact with receptors on target organs
catecholamines
released by the adrenal medulla (cait is like medusa)
cholesterol
precursor of all steroid hormones
amine hormones
can be transported on carrier proteins or unbound within the blood
hypothalamic hormones
they travel within the hypothalamic-hypophyseal portal vessels
where are TRH, GnRH, and CRH secreted from
hypothalamus
TRH, GnRH, and CRH regulate the secretion of hormones from the ___
anterior pituitary
where are posterior lobe hormones synthesized
hypothalamus
what could a lesion in the hypothalamus lead to
inhibition of myometrial contractions, increased execretion of water, reduced ability to respond to BP dropping
where is TSH synthesized from
anterior pituitary gland
where is FSH released from
anterior pituitary
what is FSH released in response to
GnRH
what facilitates sperm production in the male and maturation of ovarian follicles in females
GnRH
what is of the neuroectodermal origin
adrenal medulla (medusa had a neuroectomy - lost her mind)
what percent of the adrenal gland does the adrenal medulla make up
20%
what are the amine hormones that the adrenal medulla produces
catecholamines (cait-medusa, catecholAMINEs)
what are the two catecholamines that the adrenal medulla produces
epinephrine and norepinephrine
what does excessive ACTH stimulation cause
central obesity, hyperglycemia, muscle wasting, and hypertension
is T3 or T4 more biologically active
T3
without the Na+/I- pump, what would be affected
tissue O2 consumption, muscle growth, ventilation, cardiac output
what is crucial to CNS maturation and maintenance
T3 and T4
what triggers the synthesis of new proteins which has widespread effects throughout the body
T3 and T4