What does eGFR stand for in the context of ESRD testing?
estimated Glomerular Filtration Rate
eGFR is a key test used to assess kidney function.
ESRD assessment tools-2
dialysis symptom index
ESAS-r
In stage 5 ESRD, what is the impact of dialysis on functional status?
Does not improve functional status
What type of therapy is recommended for older, sicker patients with ESRD?
Conservative therapy
This approach focuses on managing symptoms rather than aggressive treatment.
Which dietary restrictions are advised for patients with ESRD?
- Sodium
- Phosphate
- Potassium
- Fluid
How is anemia managed in ESRD patients? -3
- Iron
- EPO injections
- Transfusion
Which medications should be stopped in ESRD patients? -5
- Beta-blockers (BB)
- ACE inhibitors/ARBs
- NSAIDs
- COX-2 inhibitors
- Diuretics
These medications can worsen kidney function.
What is the role of SGLT2 inhibitors in ESRD?
Used in transplant candidates
They help manage glucose levels and have renal protective effects.
reason to use SGLT2i (ESRD)-3
-GFR > 20
-Presence of albuminuria or heart failure
-need to delay transplant/dialysis
How is death described in the context of ESRD?
Not painful
causes for mineral bone disorder in ESRD? -2
- EPO
- Calcitriol (Vitamin D)
What happens to phosphate levels in ESRD patients?
Increased phosphate due to decreased excretion
What are the consequences of decreased calcitriol in ESRD (patho)? -4
- Decreased Calcium
- Increased PTH
- Bone demineralization
- Increased Calcium/Phosphate calcifications
These changes contribute to bone health issues.
What is the expected timeline for life after dialysis withdrawal?
Approximately 8 days to live
Patients may experience a buildup of wastes leading to a quick and painless death.
What medications are used for restless leg syndrome (RLS)? -2
- Gabapentin
- Mirapex
Which medications are recommended for pain management in ESRD? -2
- Methadone
- Fentanyl
What is deafferentation in the context of pain?
Loss of sensory input (central pain)
This condition can result in altered pain perception.
What does allodynia refer to?
Normal sensation perceived as pain
This can occur with light touch in certain pain conditions.
What is hyperesthesia?
Increased sensation
This condition can affect pain perception and response.
What is the recommended treatment for pneumonia in ESRD patients?
Urgent treatment required
What is the medication Exprex used for?
Fatigue management
What treatments are available for uremic pruritus? -5
- Capsaicin
- Mirtazapine
- Thalidomide
- Doxepin
- Dexamethasone
what happens with dialysis withdrawal -patho
no food/fluids- can’t excrete-↑buildup of wastes
quick/painless
what are the 3 types of neuropathic pain
deafferentation
sympathetic
peripheral
