1
Q
• Amoxicillin
A
- Extraction of penicillin from a fungal mould
- Broad activity against bacterial species
- Overcame limitations: sensitivity to stomach acid & resistance
2
Q
• Fexofenadine
A
- ancestor is diphenhydramine
- Overcame limitations: grogginess and sedation
3
Q
• Cefepime
A
- Extracted from acremonium mould
- Used to treat drug-resitant life-threatening infections
4
Q
• Celecoxib
A
- Overcame limitations: less damaging to gastrointestinal tract
5
Q
• Atorvastatin
A
- Used for atherosclerosis
- Overcame limitations: greater reduction in blood cholesterol
6
Q
• Atazanavir
A
- Block the enzymatic process of proteins that help with AIDS reproduction
- Overcame limitations: doesn’t disrupt lipid metabolism which causes buffalo humps
