exam 1 Flashcards

(49 cards)

1
Q

Average Daily urine output volume

A

1200 mL

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2
Q

Major organic solute present in urine; what is it and where is it produced?

A

urea, produced in the liver

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3
Q

What 2 substances can be measured in a liquid to determine if it is urine?

A

urea and creatinine

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4
Q

a decrease in urine output?

A

oliguria

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5
Q

what is the ref range for oliguria ?

A

infants: <1 mL/kg/h, children: <0.5 mL/kg/h, adults: <400 mL/day

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6
Q

increased urine excretion at night

A

nocturia

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7
Q

> 2.5 L/day in adults and >2.5 to 3 mL/kg/day in
children (high output)

A

polyuria

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8
Q

cessation of urine flow (no output)

A

anuria

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9
Q

painful urination

A

dysuria

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10
Q

in diabetes mellitus polydipsia and polyuria is caused by what?

A

caused by high blood glucose → osmotic diuresis.

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11
Q

in diabetes insipidus polydipsia and polyuria is caused by what?

A

lack of ADH or renal response to ADH

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12
Q

is diabetes mellitus specific gravity in urine is high or low?

A

high

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13
Q

is diabetes insidious specific gravity is high or low?

A

low

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14
Q

optimal test time from collection

A

2 hours

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15
Q

Turbidity in a urine specimen: likely cause

A

bacterial growth

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16
Q

group of
diseases that affect how the
body uses glucose

A

diabetes mellitus

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17
Q

body can’t
balance fluid levels

A

diabetes insipidus

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18
Q

in a unpreserved urine what happens to the pH? what is the cause?

A

increases, urea turns into ammonia, produces bacteria

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19
Q

in an unpreserved urine what happens to the glucose level? why?

A

decrease; glycolysis; bacteria use glucose

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20
Q

in a unpreserved urine what happens to bilirubin? why?

A

decreases; exposed to light

21
Q

in an unpreserved urine what happens to bacteria? why?

A

increased; multiplication

22
Q

in a unpreserved urine what happens to RBCs, WBCs, and casts ? why?

A

they dissolve or lyse due to an alkaline urine; increased pH

23
Q

what is the preferred type of preservation for a urine specimen ?

A

refrigerate (2-8C)

24
Q

what is the disadvantages of having a urine put in the refrigerator ?

A

can cause crystals; Precipitatesamorphous
phosphates and urates

25
what should you do to a urine that is refrigerated before testing it?
let it come to room temp and mix
26
what type of urine specimen is ideal for routine screening? why?
first morning specimen; most concentrated
27
is a timed urine specimen appropriate for a urine culture? why or why not?
no bc bacteria may multiply during long collection
28
When collecting a timed urine specimen, what is the first steps?
void first specimen of the day then collect the rest
29
What are the most common errors associated with timed urine collections?
Inclusion of two first-morning specimens and Inaccurate measurement
30
Which specimen type is the most sterile sample collected for urine culture?
superpubic asperate/ catheterized specimen
31
MSCC sample is what? and why do use it?
Mid Stream Clean Catch; to check for bacteria
32
When is a Chain of Custody needed and what is it?
documentation from the time of specimen collection until the time of receipt of laboratory results; legal specimens
33
What is a nephron?
functional unit of the kidney
34
Where is the glomerulus located in the kidney and what takes place there?
In cortex, inside Bowman’s capsule; filtrates plasma
35
What is Glomerulonephritis?
bleeding in the tubules of glomerulus
36
What is the Shield of Negativity in the glomerulus?
Repels molecules with a negative charge
37
What is the normal GFR for an adult?
120 mL/min
38
And what is its normal specific gravity value?
1.010
39
What does Aldosterone control in the kidney? Where?
sodium; proximal convoluted tubule (PCT)
40
Where in the nephron is the final filtrate concentrated?
collecting duct
41
What hormone controls water reabsorption into the blood stream?
ADH
42
when is ADH increased?
during dehydration
43
when is ADH decreased?
when body is fully hydrated
44
These are known as Renal Function tests.
Creatinine clearance, BUN, Serum Creatinine, Osmolality, β₂-microglobulin, cystatin C.
45
What is Creatinine a product of?
muscle metabolism (creatine)
46
why is creatinine a good substance to measure for determining the GFR?
produced at a constant rate and filtered, not reabsorbed
47
What are the units used in reporting a creatine clearance test?
mL/min
48
What is Osmolality a measure of?
the concentration of dissolved particles
49
Urine osmolality is more accurate than which test that we routinely perform on UAs?
urine specific gravity