balance between two opposing systems
normal clotting of disseminated intravascular coagulation (DIC)
involved with stopping blood flow from injured vessels
•complex cascade of clotting factors
•formation of insoluble fibrin that “plugs” vessel
hemostatic system
1st of normal clotting DIC
process in which fibrin is broken down in fibrin degradation products(FDP) and normal circulation restored
-Breaks down fibrin so it doesn’t stick together
fibrinolytic system
2nd of normal clotting DIC
DIC
•Spontaneous bleeding from gums or nose •Petechiae from minor bumps, BP cuff (capillaries are broken - see "pinpricks" •Excessive bleeding from IV, injections, catheter sites •Tachycardia •Diaphoresis
DIC signs and symptoms
Labs •decreased platelets, fibrinogen, prothrombin •prolonged PT--prothrombin time •bleeding time normal •coagulation time--no clotting •PTT increased--partial thromboplastin time
DIC signs and symptoms
• Correction of underlying cause - removal of dead fetus - treatment of pre-eclampsia, eclampsia - treatment of infection - removal of placental abruption • Packed RBCs • Fresh frozen plasma and plasma concentrates
DIC medical management
DIC medical management 2