Exam 3 Miscellaneous

Question 1

CD10 is a marker of _______.

Answer 1

B cells (particularly B-ALL)

Question 2

Hyperacute reactions (white grafts) are caused by ________.

Answer 2

antibodies

Question 3

Bruton’s is _________.

Answer 3

X-linked agammaglobulinemia (give IV Ig)

Question 4

Lower-affinity MHC binding favors ______ development, while higher MHC development favors ______ development.

Answer 4

Th2; Th1

Question 5

Job’s syndrome is _________.

Answer 5

deficient IFN-gamma production leading to increased Th2s and consequently increased IgE – sensitive cutaneous lesions

Question 6

CIVD (common variable immunodeficiency) is characterized by _________.

Answer 6

inability of B cell maturation – leading to normal B and T cells and low or no Ig