Immunomodulators

Question 1

What are HAMA?

Answer 1

Human Anti-Murine Antibodies

Question 2

ADCC is _________.

Answer 2

antibody-dependent cell cytolysis (the method of NK killing)

Question 3

What is ZMapp?

Answer 3

A combination of three monoclonal antibodies to ebola made in tobacco plants

Question 4

-omab antibodies are _________; -ximab are ______; -zumab are _______; and -umab are ________.

Answer 4

murine; chimeric; humanized; human

Question 5

Natural killer cells have no _______, but they kill cells similar to CTLs; they normally kill ________.

Answer 5

VDJ rearrangement; damaged or overly stressed cells

Question 6

What are three downsides to using immunosuppressive medications?

Answer 6

(1) increased risk of cancer; (2) increased risk of infections; and (3) toxicity