Exam 5 Flashcards

Chapters 14, 16, and 17 (32 cards)

1
Q

The type of point mutation that results in a premature stop codon is called a _________ mutation.

A

nonsense

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2
Q

__________ is the synthesis of RNA using information in the DNA.

A

Transcription

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3
Q

Stop codons are unique because they __________.

A

do not code for amino acids but instead allow a releasing factor to bind to the A site of the ribosome

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4
Q

The TATA box is a sequence with a __________ that allows for the binding of __________ and __________.

A

eukaryotic promoter; transcription factors; RNA polymerase II

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5
Q

Genetic information of eukaryotic cells is transferred from the nucleus to the cytoplasm in the form of __________.

A

RNA

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6
Q

Insertions and deletions are called __________ mutations.

A

frameshift

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7
Q

Gene expression is __________.

A

the process by which DNA directs the synthesis of proteins

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8
Q

What is the proper order of the following events in the expression of a eukaryotic gene?

  1. translation
  2. RNA processing
  3. transcription
  4. modification of protein
A

3, 2, 1, 4

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9
Q

Eukaryotic processing of the primary transcript includes __________.

A

the addition of a 5ꞌ cap, a 3ꞌ poly-A tail, and the splicing out of introns

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10
Q

An exception to the one gene–one enzyme hypothesis is __________.

A

that not all genes code for enzymes; some genes code for structural proteins such as keratin

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11
Q

The structures called snRNPs are __________.

A

part of a spliceosome

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12
Q

The sickle-cell β-globin mutation is an example of a __________.

A

missense mutation

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13
Q

Who formulated the one gene–one enzyme hypothesis?

A

Beadle and Tatum

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14
Q

The bonds that hold tRNA molecules in the correct three-dimensional shape are __________.

A

hydrogen bonds

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15
Q

One strand of a DNA molecule has the following sequence: 3-AGTACAAACTATCCACCGTC-5.

In order for transcription to occur in that strand, there would have to be a specific recognition sequence, called a(n) __________, to the left of the DNA sequence indicated.

A

promoter

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16
Q

In eukaryotic cells, a __________ by a __________ targets a growing peptide to the endoplasmic reticulum.

A

signal peptide; signal-recognition particle

17
Q

semi conservative replication

18
Q

origin of replication

19
Q

single strand binding protein

20
Q

replication fork

21
Q

leading strand

22
Q

lagging strand

23
Q

Okazaki fragment

24
Q

telomere

25
nucleotide excision repair
26
dNTP
27
topoosomerase
28
helicase
29
primase
30
DNA polymerases
31
ligase
32
telomerase