Febris

Question 1

Keypoiunts FUO

Answer 1

1. consider wrok up in light of pre- and post test probability
   2 trust the clinical clues and make a substantiated diagnosis
2. diferentiate DD based on clinic, radiology, lab results. Always formulate a leading probability diagnosis

Question 2

Definitie FUO

Answer 2

temp ≥ 38.3◦C for ≥ 3 weeks

No cause despite 3 days of admission or ≥ 3 outpatient visits.

Question 3

Temperatuur/heart rate dissociation (facets sign)

Answer 3

1 grade Celsius increase: 8-20 BPM increase

Question 4

How to come to a wrok up for FUO DD

Answer 4

• summarize complete: clinical findings, radiology workup, lab
• check WHO/RIVM website for outbreaks
• online sites fever travel.ch en Gideon online

Question 5

Extra work up FUO

Answer 5

Art. temporalis biopsyin those>55yrBone marrowexamination in case of cytopeniasEndocarditis workup (TEE)Othersonlyifclinicallyindicated(e.g. lymphnode biopsy)