Fentanyl (Sublimaze®)

Question 1

Fentanyl - Class

Answer 1

• Narcotic Analgesic

* CNS Depesant

Question 2

Fentanyl - Actions

Answer 2

• CNS depression - binds to opiate receptor sites in the CNS

* Alters the response to and perception of pain

Question 3

Fentanyl - Indications

Answer 3

• Sedation prior to intubation

* Moderate to severe pain (CP, burns, isolated extremity trauma)

Question 4

Fentanyl - Dosage/Route

Answer 4

• 25-100 mcg slow IVP (over 2-3 min)

* May repeat in 30 min. prn

Question 5

Fentanyl - Side Effects

Answer 5

• Decreased LOC
• Paradoxical excitation
• Respiratory depression &/or arrest
• Arrhythmias, bradycardia, hypotension
• N/V

Question 6

Fentanyl - Contraindications

Answer 6

• Known hypersensitivity to the drug
• MAO Inhibitors within 14 days
• Myasthenia Gravis

Question 7

Fentanyl - Special Information

Answer 7

• May produce severe or fatal reactions when given to pts on MAOI’s
• Additive CNS depression with alcohol, antidepressants, antihistamines, or sedative/hypnotics
• Monitor VS & ECG continuously
• Naloxone will reverse overdose effects
• Assess effectiveness of administration with reassessment of pain, respiratory status & sedative effects
• Use with caution in pts with head trauma, increased ICP, undiagnosed abdominal pain, elderly, debilitated
• Reduce dosage for pts with COPD, respiratory problems, or hepatic/renal insufficiency

Question 8

Fentanyl - Pediatric Note

Answer 8

• Refer to Pediatric Drug Guide

* For children 1-12 yrs: 1-2 mcg/kg slow IVP/IM