Final😳 Flashcards

(146 cards)

1
Q

Structural Level of Body Organization

A

Chemical → Cellular → Tissue → Organ → System → Organism

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2
Q

Body Planes/Sections

A

Frontal
Transverse
Midsagittal
Parasagittal
Oblique

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3
Q

Right upper quadrant

A

Liver, gallbladder, duodenum, right kidney, ascending colon

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4
Q

Left upper quadrant

A

Spleen, stomach, pancreas, left kidney, transverse/descending colon

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5
Q

Right lower quadrant

A

Appendix, right ovary, right spermatic cord, ureters, ileum, cecum

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6
Q

Lower left quadrant

A

Sigmoid colon, jejunum, left ovary, left spermatic cord

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7
Q

Negative feedback loop

A

Reverses change
Thermoregulation
Blood sugar regulation
Blood pressure regulation

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8
Q

Positive feed back loop

A

reinforces/strengths a change
Pregnancy
Lactation
Blood clotting

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9
Q

Major elements 96%

A

Oxygen 64%,
Carbon
Hydrogen
Nitrogen

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10
Q

Lesser elements 3.6%

A

Calcium
Potassium
Phosphorus
Sulfur
Sodium
Chlorine
Magnesium
Iron

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11
Q

Trace elements 0.4%

A

Copper
Iodine
Selenium
Zinc

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12
Q

Ionic bonds

A

Donate & accept electrons
Cation (+) vs. Anion (-)
Solid; mainly in teeth and bones
Electrolytes formed when compound breaks apart into + or - ions in solution

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13
Q

Covalent bonds

A

Share electrons
When two or more atoms share valence electrons

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14
Q

Covalent polar

A

unequal sharing, hydrophilic

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15
Q

Covalent non polar

A

equal sharing, hydrophobic, most common

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16
Q

Hydrogen bonds

A

Weak
Attraction between a slightly negative and slightly positive molecule
Create surface tension, gives water cohesion
Stabilizer of larger molecules

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17
Q

Monosaccharides

A

Simple sugars that contain from 3-7 carbon atoms

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18
Q

Disaccharides

A

Simple sugars formed from the combination of two monosaccharides by dehydration synthesis

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19
Q

Polysaccharides

A

Forms tens to hundreds of monosaccharides joined by dehydration synthesis

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20
Q

Fatty acids

A

Used to synthesize triglycerides and phospholipids or catabolized to generate ATP

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21
Q

Triglycerides

A

Protection, insulation, energy storage.

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22
Q

Phospholipids

A

Major lipid component of cell membranes.

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23
Q

Structural protein

A

Form structural framework of various parts of body

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24
Q

Regulatory proteins

A

Function as hormones that regulate various physiological processes, control growth and development; as neurotransmitrers,
mediate responses of nervous svstem.

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25
Contractile proteins
Allow shortening of muscle cells, which produces movement.
26
Immunological protein
Aid responses that protect body against foreign substances and invading pathogens.
27
Transport proteins
Carry vital substances throughout body.
28
Catalytic proteins
Act as enzymes that regulate biochemical reactions.
29
Amino acids are
“building blocks”, basic units of protein. Peptides, polypeptides
30
Plasma membrane
Flexible yet sturdy barrier that surrounds and contains the cytoplasm of the cell. Functions include isolation, sensitivity and regulation of exchange in the environment, and structural support
31
Lipid bilayer
two back to back layers made of three types of lipid molecules
32
Lipid molecules
Phospholipids – 75% Cholesterol – 20% Glycolipids – 5%
33
Ion channel (integral)
Forms a pore through which a specific ion can flow to get across membrane
34
Carrier (integral)
Transports a specific substance across membrane by undergoing a change in shape
35
Receptor (integral)
Recognizes specific ligand and alters cell's function in some way
36
Enzyme (integral and peripheral)
Catalyzes reaction inside or outside cell (depending on which direction the active site faces)
37
Linker (integral and peripheral)
Anchors filaments inside and outside the plasma membrane, providing structural stability and shape for the cell. May also participate in movement of the cell or link two cells together
38
Cell identity marker (glycoprotein)
Distinguishes your cells from anyone else's (unless you are an identical twin)
39
Mitochondria
Produces ATP = energy currency. Temporarily stores. Site of cellular respiration
40
Golgi complex
modifies molecules furthers, then sorts and packages them for transport to their destinations
41
Rough endoplasmic reticulum
contains ribosomes* synthesizes glycoproteins and phospholipids that are transferred to cellular organelles, inserted into plasma membrane, or secreted during exocytosis.
42
Smooth endoplasmic reticulum
lacks ribosomes* synthesizes fatty acids and steroids, inactivates or detoxifies drugs, removes phosphate group from glucose-6-phosphate, and stores and releases calcium ions in muscle cells
43
Lysosome
Waste disposal system
44
Active transport in Vesicles — Receptor mediated Endocytosis:
Active process in which a cell expends energy (ATP) to move a substance across the membrane against its concentration gradient
45
Endocytosis
movement of substance to the inside of a cell
46
Exocytosis
Movement of substances out of a cell
47
Phagocytosis
“cell eating”; movement of a solid particle into a cell after pseudopods engulf it to form a phagosome
48
Pinocytosis
“cell drinking” ingestion of liquid into a cell
49
Epithelial tissue
Densely packed sheets of cells Little to no ECM Many cell junctions Avascular, but has a nerve supply Mitosis occurs frequently
50
Simple squamous
alveoli of lungs
51
Simple cubodial
thyroid gland
52
Simple columnar
small intestine
53
Stratified squamous
Epidermis
54
Stratified cubodial
sebaceous glands, sweat glands, ducts
55
Pseudostratified (ciliated)
trachea, bronchi
56
Transitional/urothelium
Urinary bladder
57
Connective tissue
Widely spaced cells Lots of ECM = ground substance + fibers Highly vascularized and nerve supply present (with the exception of Hyaline cartilage) Binds, supports, and strengthens other body tissues
58
Embryonic
mesenchyme or mucous
59
Loose areolar
Most common
60
Loose areolar location
Subcutaneous layer, Blood vessels, Nerves, Organs
61
Loose areolar function
strength, elasticity, support
62
Loose adipose
adipocytes, stores triglycerides
63
Loose adipose location
areolar tissue, subcutaneous layer, heart, kidneys, yellow bone marrow, joints, eyeball
64
Loose adipose function
reduce heat loss, energy reserve, supports organs
65
Loose reticular
Reticular fibers and reticular cells
66
Loose reticular location
stroma of liver, spleen, lymph nodes, red bone marrow, reticular lamina, blood vessels, muscles
67
Loose reticular function
stroma of organs, binds smooth mm, filters blood cells and microbes
68
Dense regular
Forms extracellular matrix, collagen fiber bundles; fibroblasts rows between
69
Dense regular location
tendons, ligaments, aponeurosis
70
Dense regular function
Strong attachment between structures. Tissue withstands pulling along fibers axis
71
Dense irregular
Collagen fibers random arranged with a few fibroblasts
72
Dense irregular location
Fasciae, Dermis, Pericardium, Periosteum, Perichondrium, Joint/membrane, Kidneys/liver/testes/lymph nodes/heart
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Dense irregular function
Provides tensile strength in many directions
74
Dense elastic
Fibers with fibroblasts, yellowish color
75
Dense elastic location
Lung tissue, Arteries, Trachea/bronchial tubes/vocal cords, Penis/vertebrae ligaments
76
Dense elastic function
Stretches organs, Recoil
77
Compact bone tissue
Osteons
78
Spongy bone tissue
Trabeculae
79
Blood liquid
Plasma
80
Lymph liquid
lymphocytes (WBC’s)
81
Mucous membrane
opens to the exterior; possess goblet cells that secrete mucous Esophagus
82
Serous membrane
never open to the exterior
83
Meninges
pleural membrane that surrounds the brain and spinal cord
84
Synovial membrane
membranes that encapsulate joints, only connective tissue membrane
85
Keratinocytes
Most abundant, makes up 90% of epidermis Spikey Filled with keratin protein – coated in hydrophobic molecules Need protection from UV damage Lamellar granules give waterproofing to skin
86
Melanocytes
Makes up 8% - only in stratum basale layer Tentacle – like Melanin granules release by exocytosis; taken up by keratinocytes Protects from UV damage All bodies have same number of melanocytes Number of melanin granules made = determines skin colour Melanin granules determine skin pigment, lacking melanin = albinism
87
Corneum
Superficial
88
Lucidum
Thick skin only
89
Granulosum
keratohyalin and lamellar granules
90
Spinosum
melanocytes & langerhan cells
91
Basale
produces keratinocytes, melanocytes, tactile epithelial cells, and discs
92
Papillary region
Superficial portion of dermis (1/5th) Areolar connective tissue with thin collagen and elastic fibers Contains dermal ridges (dermal papillae) housing blood capillaries, corpuscles of touch and free nerve endings, capillary loops
93
Reticular region
Deeper portion of the dermis (4/5th) Dense irregular connective tissue with thick collagen and some elastic fibers Spaces between fibers contain adipose cells, hair follicles, nerves, sebaceous glands and sudoriferous (sweat) glands
94
Sebaceous gland
Prevent hairs from drying out, prevent water loss from skin, keep skin soft, inhibit growth of some bacteria
95
Eccrine glands
Regulation of body temp, waste removal, stimulated during stress
96
Apocrine glands
Stimulated during emotional stress and sexual excitement
97
Ceruminous glands
Impede entrance of foreign bodies and insects into external ear canal, waterproof canal, prevent microbes from entering cells
98
Superficial Wound Healing
Occurs when superficial wounds affect only the epidermis No Scar
99
Deep Wound Healing
Occurs when an injury extends into dermis and subcutaneous layer Leaves behind scar Fibrosis ex. Keloid scars (overgrowth of skin)
100
4 deep wound healing phases
Inflammatory → migratory phase → proliferative phase → maturation phase
101
Inflammatory phase
Information blood clot forms in the wound and loosely unties wound edges
102
Migratory phase
Clot becomes a scab, epithelial cells migrate beneath scab to bridge wound
103
Proliferative phase
Growth of epithelial cells beneath scab + continued growth of blood cells
104
Maturation phase
Scab falls off once epidermis is restored to normal thickness
105
Functions of skeletal tissue
Provide support Protects the internal organs Assists body movements – in conjunction with muscles Mineral homeostasis – stores and releases calcium and phosphorus Participates in blood cell production from red bone marrow – hematopoiesis Stores triglycerides in adipose cells of yellow marrow
106
Osteoprogenitor
Bone stem cells able to differentiate into other types of cells Undergo cell division when stimulated Cells develop into osteoblasts (gap junctions)
107
Osteoblasts
Bone building cells Synthesize/secrete collagen fibers Forms bone extracellular matrix, become osteocytes Deposits calcium/phosphorus from food Initiate calcification
108
Osteocytes
*most abundant* Mature, primary cells in bone tissue Maintains bone tissue/metabolism and nutrient exchange in blood
109
Osteoclasts
Carves out bone, absorbing Large cell; breaks down extracellular matrix Develops from white blood cells Remodels and bone resorption; calcium release Ruffled border – folded plasma membrane; secretes digestive enzymes to underlying extracellular matrix that dissolves, releasing calcium to blood
110
Spongy Bone - Trabecular
Lightweight interior bone. Always beneath a layer of compact bone. Provides tissue support and flexibility for tendon insertion
111
Compact Bone - Cancellous
Strongest tissue. Provides protection and support. Resists stresses of weight and movement Makes up: Diaphysis of long bone – Under periosteum
112
Epiphyses
Both ends of bone
113
Diaphysis
Shaft
114
Metaphysis
between diaphysis and epiphysis containing a growth plate on each end
115
Epiphyseal line
Remanent of the growth plate in adults
116
Articular cartilage
Thin layer of hyaline cartilage covering both epiphyses where the bone forms a joint
117
Medullary cavity
Hollow space within diaphysis; containing bone marrow, lightens the weight of the bone.
118
Periosteum
Surrounding diaphysis
119
Endosteum
Thin membrane lining the medullary cavity
120
Muscle
organ - Many fascicles - Wrapped in epimysium
121
Muscle fascicles
tissue - Bundle of muscle fibers - Wrapped in perimysium
122
Muscle fiber
cell - Many mesodermal cells (myoblasts) - Wrapped in endomysium
123
Myofibril
contractile organelle - Made of repeated segments of sarcomeres; in a muscle fiber/cell
124
Sarcomere
contractile - Compartments where filaments are arranged inside myofibril
125
Endomysium
Surrounds each muscle fibre
126
Perimysium
Surrounds muscle fascicles
127
Epimysium
Surrounds entire muscle organ
128
Sarcoplasmic Reticulum
ER that stores and releases Ca2+ into the sarcoplasm when stimulated by a neuron.
129
Contractility
Ability of muscular tissue to contract forcefully when stimulated by an action potential. Pulls bone where muscle is shortened.
130
Extensibility
Ability of muscular tissue stretch, within limits, without being damaged
131
Elasticity
Ability of muscular tissue to return to its original length and shape after contraction/extension
132
Excitability
Ability to respond to stimuli by producing electrical signals – action potentials
133
Actin (thin) = troponin + tropomyosin
Has myosin binding site where the myosin head of thick filament binds during contraction, can block myosin with regulatory protein
134
Myosin (thick) = 2 head + 1 tail
Binds to myosin binding sites on actin during contraction. Myosin pulls actin in contraction (gets blocked by regulatory proteins).
135
Regulatory
help switch contraction process on and off, allows myosin to bind to actin when somatic neurons stimulate a muscle fiber
136
Tropomyosin
Blocks myosin binding site so myosin cannot bind to actin
137
Troponin
Moves tropomyosin away from myosin-binding sites on actin molecules
138
Titin
Connects Z disc to M line of sarcomere
139
Myoglobin
gives red color to mm
140
Skeletal muscle
voluntary Moves bones Multinucleated Striated Stimulated from somatic motor neurons Limited capacity for regeneration due to satellite cells
141
Cardiac Muscle
Involuntary Only in heart wall 1 nucleus Striated Intercalated discs - desmosomes and gap junctions; electrical signals pass through
142
Smooth muscle
Involuntary Spindle-shaped/fusiform 1 nucleus Not striated Sends signals – sympathetic/parasympathetic nervous system
143
Motor unit
1 somatic motor neuron and branches + all the muscle fibers it innervates FEW motor units = WEAK muscle contraction - recruited first MANY motor units = STRONG muscle contraction - get signal last
144
slow oxidative
in marathon runners. Least powerful muscles
145
fast glycolic
weight/powerlifters. Anaerobic glycolysis
146
fast oxidative-glycolytic
Walking and sprinting