viral ligand of Flavi
E protein
entry in Flavi
RME
C
nucleocapsid
prM
precursor glycoprotein cleaved
M
transmembrane protein for entry
E
membrane protein
(viral ligand),
facilitates release
NS2B & NS3
cleavage of polyprotein
NS 3
has helicase & protease activities
NS4A & 4B
co-factor for replication
NS5
RdRp