What does FODMAP stand for?
Fermentable Oligosacchardies, Disaccharrides, Monosaccharides and Polyols
Oligosacchardies - Fructans
Chain of fructose molecules with a glucose terminal end (varying length)
Sub-groups of fructans:
Fructo-Oligosacchardie (<10)
Oligofructose (2-8)
Inulin (2-60)
Oligosacchardies - Fructans (digestion and absorption)
Poorly absorbed in all people
Lack of enzyme to break B2-1 bond
Pass through small intestine
Readily fermented by gut bacteria in large intestine
Oligosacchardies - Fructans (average intake in UK)
4g/d (3.6g/d IBS)
Oligosacchardies - Galacto-Oligosacchardies
Chain of galactose molecules with a sucrose terminal end
Raffinose (1 ga)
Stachyose (2 ga)
Verbascose (3 ga)
Oligosacchardies - Galacto-Oligosacchardies (digestion and absorption)
Poorly absorbed in all people
Lack of enzyme a-galactosidase
Pass through small intestine completely intact
Readily fermented by gut bacteria in large intestine
Oligosacchardies - Galacto-Oligosacchardies (average intake UK)
2g/d IBS
Disacchardies - Lactose
Two sugar unit
Glucose + galactose
Disacchardies - Lactose (digestion and absorption)
Poorly absorbed in some peoples due to lack of enzyme lactase
Lactase hydrolyses lactose into monosaccharides
Osmotic pull - draws water into small intestine as it moves through
Fermented by gut bacteria in large intestine
Disacchardies - Lactose (deficiencies)
Primary lactose deficiency - genetic fault
Secondary lactase deficiency- due to illness or injury
Developmental - premature babies
Congenital - genetic fault
Disacchardies - Lactose (average intake UK)
7g/d IBS
Monosaccharide - Fructose
One sugar unit
Monosaccharide - Fructose (digestion and absorption)
Passes through gut via GLUT5 receptor
Capacity for absorption is variable
Not well absorbed in small intestine
Draws in water as moves down gut
Majority makes it to large intestine where it is fermented by bacteria
Glucose aids absorption of fructose in small intestine via GLUT2 receptor
Monosaccharide - Fructose (average intake UK)
17g/d IBS
What is considered a high fructose load in one sitting?
More than one handful of safe fruit
Fruit juice
Dried fruits in large amounts
Added fructose
Foods high in sucrose (e.g. fizzy juice)
Polyols - sugar alcohols
Hydrogenated carbohydrates
Alcohol group
Predominantly monosaccharides
Disaccharides
Polyols - sugar alcohols (digestion and absorption)
Some absorbed in small intestine via passive absorption only
Absorption affected by intestinal transit time
Tolerated in low concentration but at high concentrations won’t be very well absorbed
Certain types may be tolerated better
Polyols - sugar alcohols (average intake UK)
<1g/d IBS
Symptoms caused by FODMAPS
Motility changes
Bloating
Pain and discomfort
Wind
Cut off for high FODMAP
Fructans >0.2g per portion
Lactose >4g per portion
Fructose >0.5g in excess of glucose per 100g or >3g per portion
Polyols >0.3g per portion
3 stages of FODMAP diet
Restriction
Reintroduction
Personalisation (long-term management)
Some people may not need to restrict … and … as bodies can absorb these quite well
Lactose or fructose
Two approaches of low FODMAP diet - Top down
Restrict FODMAPS for 4-8 weeks
Reintroduction of foods to find personal tolerance
Emphasis on return to normalised diet
Two approaches of low FODMAP diet - Bottom up
Reduce specified high FODMAP foods
Restriction over a set period
Further restrictions only used if no improvements of symptoms in response