Fondaparinux

Question 1

What is the mechanism of action of faundaparinaux?

Answer 1

Inhibits factor Xa only

Question 2

When is fondaparinux indicated for use?

Answer 2

First-line therapy to improve revascularisation and prevent intracoronary thrombus progression in ACS

Question 3

What are common adverse effects of fondaparinux?

Answer 3

• Bleeding
• Anaemia
• Purpura

Question 4

What dose of fondaparinux should be used to treat unstable angina/NSTEMI?

Answer 4

2.5 mg once daily for up to 8 days by SC injection

Question 5

What dose of fondaparinux should be given to someone with a STEMI?

Answer 5

2.5 mg IV for first day, then 2.5 mg once daily for up to 8 days (or until discharge)