Gametogenesis Problems

Question 0

What becomes increasingly frequent after age 35?

Answer 0

Chromosomal abnormalities increase

- due to lengthy dormant period for the primary oocyte

Question 1

What is the ideal maternal age for reproduction?

Answer 1

18-35

Question 2

What is nondisjunction?

Answer 2

Failure of homologous chromosomes to separate during meiosis

- occurs in either meiotic divisions
- resultant gamete may have 24 or 22 chromosomes

Question 3

What is trisomy?

Answer 3

Zygote having 47 chromosomes

- results from union of gametes having 24 and 23 chromosomes
- most common is trisomy 21 (Down Syndrome)

Question 4

What is Monosomy?

Answer 4

Zygote having 45 chromosomes

- results from union of gametes having 22 and 23 chromosomes
- Turner Syndrome (45, X) is only monosomy compatible with life