Why is capacitation required?
~7hr process of conditioning sperm so they are able to fertilize
Are freshly ejaculated sperm capable of fertilizing an oocyte?
NO!
What is the process of capacitation?
process of conditioning sperm
How long does capacitation take?
~7hrs
Where does capacitation occur?
promoted in the uterus and oviducts by secretory factors produced there
What changes occur in the sperm during capacitation?
enzymatic removal of glycoproteins from the sperm and the acrosome surface
What happens to acrosome membrane during acrosome reaction?
perforations develop in the acrosome membrane
When does a change in the acrosome membrane occur?
What does Hyaluronidase facilitate?
Facilitates penetration through corona radiata
What does Acrosin facilitate?
Facilitates penetration through zona pellucida