CNS anomaly most specific to DM
Caudal regression
MC medical complication of pregnancy
GDM
Insulin resistance caused by inc levels of
HpL and insulinase
Classification of DM complicating pregnancy A1 A2 B C D F R H
Gestational FPG105 2hPPG>120 insulin Type I DM Nephropathy Retinopathy Heart
Low risk
No known DM in first degree <25 yo N weight N glucose testing N obstetric outcome
Average risk
24-28 w
Southeast Asian
Hispanic
African
Native American
High risk
ASAP
24-28
Obesity Strong FH DM II Prior gestational DM Glucosuria Prev infant >4000g POH
Screening test
50g OGCT
Confirmatory test
100g OGTT
Fasting glucose
1 hr OGTT
2 hr
3 hr
95
180
155
140
MC maternal complication of GDM
Polyhydramnios
MC growth disorder in DM
Fetal macrosomia
Start insulin therapy when
FPG>105 despite diet therapy
Post partum DM evaluation
75 g OGTT after 6-12 w
FPG 140
1 hr 200
2 hr 200