Principal mediator of Quiescence
Progesterone
Phases of Parturition
Quiescence
Activation
Labor
Recovery
Quiescence Uterus Cervix Contractions Pains Events
Unresponsive Softening Very low intensity Irregular Lower abdomen Braxton Hicks
Quiescence
Estrogen
Promotes synthesis of progesterone cell receptors
Activation Uterus Cervix Contractions Pains Events
Responsive to uterotonins Inc contractility, contraction assoc proteins, gap junctions and oxytocin receptors Ripening Inc frequency of painless contractions Ant abdominal wall and lower back LUS Lightening
Principal mediator of activation
Estrogen
Parturition
Stages
Cervical effacement and dilatation
Fetal expulsion
Placental separation
Source of uterotonins
Amnion
Decidual parietalis
Produced endothelin-1 and prostaglandin
Chorion
Principal mediator of parturation
Prostaglandin
Principal mediator of resolution
Oxytocin
Active phase
4 cm