Genetic Inheritance Patterns

Question 1

What are some examples of diseases with an autosomal dominant inheritance pattern?

Answer 1

• Familial hypercholesterolaemia
• Polycystic kidney disease
• Hereditary spherocytosis
• Marfan syndrome
• Huntington’s disease

Question 2

What are some examples of diseases with an autosomal recessive inheritance pattern?

Answer 2

• Sickle cell disease
• Cystic fibrosis
• Tay-Sachs disease
• Wilson’s disease
• Hereditary haemochromatosis
• Phenylketonuria
• Crigler-Najjar syndrome

Question 3

What are some examples of diseases with an X-linked recessive inheritance pattern?

Answer 3

• Red-Green Colour Blindness
• Duchenne’s Muscular Dystrophy
• Becker’s Muscular Dystrophy
• Fragile X syndrome
• Haemophilia A and B
• Hunter’s Syndrome
• G6PD Deficiency

Question 4

What are some examples of diseases with an X-linked dominant inheritance pattern?

Answer 4

• Vitamin D Resistant Rickets
• Rett’s Syndrome

Question 5

What is the inheritance pattern of familial hypercholesterolaemia?

Answer 5

Autosomal dominant

Question 6

What is the inheritance pattern of sickle cell disease?

Answer 6

Autosomal recessive

Question 7

What is the inheritance pattern of cystic fibrosis?

Answer 7

Autosomal recessive

Question 8

What is the inheritance pattern of red-green colour blindness?

Answer 8

X-linked recessive

Question 9

What is the inheritance pattern of polycystic kidney disease?

Answer 9

Autosomal dominant

Question 10

What is the inheritance pattern of Haemophilia A?

Answer 10

X-linked recessive

Question 11

What is the inheritance pattern of Tay-Sach’s disease?

Answer 11

Autosomal recessive

Question 12

What is the inheritance pattern of Duchenne’s muscular dystrophy?

Answer 12

X-linked recessive

Question 13

What is the inheritance pattern of hereditary spherocytosis?

Answer 13

Autosomal dominant

Question 14

What is the inheritance pattern of Wilson’s disease?

Answer 14

Autosomal recessive

Question 15

What is the inheritance pattern of Marfan’s?

Answer 15

Autosomal dominant

Question 16

What is the inheritance pattern of hereditary haemochromatosis?

Answer 16

Autosomal recessive

Question 17

What is the inheritance pattern of Haemophilia B?

Answer 17

X-linked recessive

Question 18

What is the inheritance pattern of fragile X syndrome?

Answer 18

X-linked recessive

Question 19

What is the inheritance pattern of Huntinton’s disease?

Answer 19

Autosomal dominant

Question 20

What is the inheritance pattern of phenylketonuria?

Answer 20

Autosomal recessive

Question 21

What is the inheritance pattern of Hunter’s syndrome?

Answer 21

X-linked recessive

Question 22

What is the inheritance pattern of Crigler-Najjar syndrome?

Answer 22

Autosomal recessive

Question 23

What is the inheritance pattern of G6PD deficiency?

Answer 23

X-linked recessive