Genetic Mapping

Question 1

What is a 2-point analysis?

Answer 1

1 locus is the disease locus and the other point is a marker

Question 2

Informative meiosis

Answer 2

A meiosis is informative when recombinants can be determined

Question 3

What is the main point of genetic mapping?

Answer 3

That one of the alleles of that marker will always co-segregate with the disease because it is on the same chromosome that is inherited by affected individuals

Question 4

Why will the allele be different in different pedigrees?

Answer 4

because the mutation may not be the same on a molecular level

Question 5

Identical by descent allele

Answer 5

Same allele because the same chromosome is inherited

Question 6

identical by state

Answer 6

Same allele on the same marker so not necessarily reflecting the same chromosome