What does a mature mRNA consist of?
addition of methylated cap of the 5’, polyA tail on the 3’ end, 5’ and 3’ untranslated region
What was the human genome project?
A plan to determine the complete human genome sequence
What is the human genome size?
3.2 x 10^9 bp
What is the variation of DNA amongst different people?
Varies only 0.1% or less: 3 million letters would differ between individuals
What is the 100,000 genomes project?
Aimed to find what are the positions in DNA that change among individuals (SNPs)
What is the All of Us project?
Sequence DNA of a million people
Chi squared testing
sum (O-E)^2/E