genetics

Question 1

how many genes do we have

Answer 1

21-25000

Question 2

how much of our DNA is made up of genes

Answer 2

1-2%

Question 3

what is the promotor region for translation

Answer 3

TATA box - 5’

Question 4

which direction is DNA replication

Answer 4

5’–>3’

Okazaki fragments in lagging strand

Question 5

what happens to the similarity of our genome with each degree of relationship

Answer 5

each degree of relationship = halves the genes

Question 6

when do you often seen autosomal recessive diseases

Answer 6

mating of related individuals = consanguinity

Question 7

what are the features of an autosomal dominant disease

Answer 7

• vertical transmission
• lack of skipped generations
• equal males and females
• may see reduced penetrance
• may see incomplete dominance
• may see variability in expressivity

Question 8

what is reduced penetrance

Answer 8

dont show the phenotype

Question 9

what is genetic heterogeneity

Answer 9

different genotypes are associated with the same phenotype