Gentamicin

Question 1

what is gentamicin

Answer 1

a type of aminoglycoside antibiotic

Question 2

how is gentamicin given

Answer 2

parentally or topically

Question 3

what are the two adverse effects of gentamicin

Answer 3

ototoxicity
nephrotoxicity

Question 4

what drug increases the risk of gentamicin nephrotoxicity

Answer 4

furosemide

Question 5

what is a contraindication for gentamicin use

Answer 5

myasthenia gravis

Question 6

what is it important to measure in gentamicin use

Answer 6

due to the significant ototoxic and nephrotoxic potential of gentamicin it is important to monitor plasma concentrations

Question 7

what levels are measured in gentamicin use

Answer 7

both peak (1 hour after administration) and trough levels (just before the next dose) are measured

Question 8

what should happen if the trough (pre-dose) level is high

Answer 8

the interval between the doses should be increased

Question 9

what should happen if the peak (post-dose) level is high

Answer 9

the dose should be decreased