What are FODMAPs
fermentable Oligosaccharides, disaccharides, monosaccharides and polyols
FODMAPs: F = ?
Fermentable: not absorbed in upper GIT; feeds the microflora
FODMAPs: O = ?
Oligosaccharides:
1. fructo-oligosaccharides s (fructans)
wheat, Jerusalem artichokes, globe artichokes, onions, leeks, yacon, asparagus, etc…
2. Galacatooligosaccharides (raffinose and stachyose)
legumes, cabbage, Brussel sprouts, green beans
FODMAPs: D = ?
Disaccharides,
◦ lactose (in malabsorbers)
FODMAPs: M = ?
Monosaccharides,
◦ fructose (in malabsorbers)
FODMAPs: AP = ?
And Polyols
◦ sorbitol, lactitol, xylitol, and other sugar alcohols
GERD prevalence in Western Nations
10-20%
Gerd S and S
1.Sensation of heartburn
2.Regurgitation
3.Extraoesophageal manifestations:
◦ Chronic cough
◦ Halitosis
◦ Dental erosions
◦ Chronic laryngitis
What causes GERD?
Lower oesophageal sphincter (LOS)
incompetence
Causes of GERD?
1.LES incompetence
2.delayed gastric emptying
3.impaired esophageal acid clearance
4.decreased salivation
5.presence of hiatal hernia
» reflux of gastric contents into esophagus»mucosal damage/symptoms
GERD contributing factors?
GERD dietary contributing factors?
OTHER: diet related factors for GERD?
GERD: Protective Role of Helicobacter pylori?
the presence of H. pylori infection in the
stomach plays a protective role against the
development of the most severe forms and
complications of GORD (Pereira-Lima et al, 2004), including
Barrett’s oesophagus
Is GERD caused by too little gastric acid?
NO. The majority of GORD sufferers in this study had
normal HCL secretion.
Is LHBT a reliable dx tool for SIBO?
NO
LHBT =
lactose hydrogen breath test
Conventional treatment for GERD?
Acute adverse events with PPIs/H2RAs?
diarrhoea
nausea
abdominal pain
headaches
Longer-term risks with PPIs/H2RAs?
increased risk of gastroenteritis
SIBO
stomach bacterial overgrowth - due to decr HCL
pneumonia
spinal fracture
vitamin and mineral malabsorption - due to decr HCL
Natural Medicine Tx Aims for GERD?
Relieve symptoms
Decrease oesophageal inflammation & promote oesophageal healing
Eliminate/minimise exacerbating factors
◦ address dietary factors
◦ address lifestyle factors
Promote antioxidant defences
Improve salivary gland function/oesophageal acid clearance
Speed gastric emptying
Prevent oesophageal cancer
Support the nervous system
GERD: tools to relieve heartburn pain (which is paramount)
Melatonin mechanisms of action for GERD?
Options for GERD to Decrease oesophageal inflammation &
promote oesophageal healing?